Research Scientist / Senior Research Scientist, Assay Development (Diagnostics) Job at SiPhox Health, Burlington, MA

R0hzYm1WaUl6bDBVMTFhaHAwczJONGRIVmc9PQ==
  • SiPhox Health
  • Burlington, MA

Job Description

About the job

SiPhox Health, a Khosla Ventures, Intel Capital, and Y Combinator-backed startup, is commercializing next-generation diagnostics using silicon photonics, a platform technology for optics miniaturization that has revolutionized the data center industry over the last two decades. Our chip-based solution combines state-of-the-art biochemistry, photonics, electronics, and microfluidics to provide the power of large laboratory instruments in a compact device.

We are seeking an exceptional scientist to be part of an exciting, externally funded project to push the boundaries of continuous monitoring of complex biological systems. Our goal is to develop state-of-the-art sensor technology that will revolutionize fields ranging from medical diagnostics to biomanufacturing. If you are passionate about driving innovation and making a tangible impact in biotechnology, we invite you to join us as we explore this new frontier.

Role Overview

We are looking for a Research Scientist or Senior Research Scientist in Assay Discovery to drive the development of a menu of new immunoassay targets targeting continuous monitoring applications. This will involve screening antibody candidates on surrogate systems (SPR, BLI) and optimizing assay conditions on the SiPhox platform. The successful candidate will collaborate with our engineers, process development, and product development teams to build this expanded menu and help bring it through validation.

Responsibilities

  • Design and execute immunoassay experiments; generate and interpret data
  • Summarize relevant work into written reports and presentations
  • Collaborate across the organization on systems integration with SiPhox instrumentation
  • Validate assays and assist when needed with the commercialization process for the developed menu of markers
  • Collaborate with the process and chemistry team to ensure the development of robust and scalable processes for assay manufacturing and quality control
  • Note: SiPhox is a fast-paced startup, and this is a fully in-person job that can sometimes require working long hours to meet deadlines

Qualifications

  • PhD + 3 years or MS + 6 years of industry experience in biochemistry, biophysics, analytical chemistry, bioengineering or a related discipline
  • Experience with immunoassay development required
  • Knowledge of diagnostic product development and instrument systems required
  • Familiarity with in vitro diagnostic (IVD) assay development, ISO 13485, and 21 CFR 820 required
  • Experience working as part of a multi-disciplinary team required
  • Able to resolve complex technical problems independently
  • Working knowledge and practical ability in a variety of complex laboratory procedures, established techniques, instruments and equipment
  • Attention to detail and good record keeping skills
  • Proven key contributions to development projects and marketed products
  • Familiarity with statistical principles applicable to assessment of assay performance
  • Familiarity with standards applicable to assay validation preferred
  • Experience in computational analysis of data sets using general purpose programming language (such as Python, R, or Matlab) preferred
  • Experience with CLIA a plus
  • Experience with point-of-care, at-home, and/or wearable devices is a plus
  • Experience with label-free sensors is a plus
  • Experience with biochips, microarrays, and microfluidics is a plus

Additional qualifications for Senior Research Scientist

  • PhD and 4+ years or MS and 6+ years of industry experience in biochemistry, biophysics, analytical chemistry, bioengineering, or a related discipline

Personal Characteristics

  • Sets and achieves ambitious goals, delivering outstanding and measurable results
  • Exhibits absolute personal integrity and credibility; acts with a small-team mentality but delivers outsized results
  • Passionate about excellence
  • Willing to take risks and challenge conventional solutions
  • Creative thinker, able to think outside the box and strategically

Job Tags

Similar Jobs

PlayCore

CNC Router Operator Job at PlayCore

Summary Produces both plastic and wood parts by programming, setting up, and operating both numerical control CNC Machines, packaging, assembly, loading, mechanical drills, saws, sanders, and other hand tools while maintaining quality and safety standards. Enter production...

EAM-Mosca Corp.

Parts Associate/Picker-Packer/Receiving Job at EAM-Mosca Corp.

 ...holiday for this). Processing of company outgoing mail and miscellaneous packages Profile and Background: Experience in a pick and pack operation preferred. Stable work history a must. Must be able to lift up to 50Lbs. Ability to read and communicate in... 

International

Environment, Health and Safety Manager Job at International

 ...WE'RE INTERNATIONAL COMMITTED TO THE ROAD AHEAD We are seeking an Environmental Health and Safety Manager to join the International Motors team at our state-of-the-art 1 million sq. ft. production facility in San Antonio, TX, where we manufacture class 6-8 and electric... 

Somewhere

Biomedical Engineer Job at Somewhere

 ...Job Title: Biomedical Engineer Location :100% Remote (Open for LATAM region) Job Type :Full-Time Salary : $2,800 to $4,000 Usd Based on Experience Type of Contract : Independent Contractor Agreement Key Responsibilities : Design and Development... 

General Dynamics Information Technology

DevOps Engineer, Sr Job at General Dynamics Information Technology

 ...expertise to protect our country from threats. Job Description Deliver simple solutions to complex problems as a DevOps Engineer at GDIT. Here, youll tailor cutting-edge solutions to the unique requirements of our clients. With a career in application development, you...