Job Description

Senior/Principal Scientist, Protein Science - Permanent - Indianapolis, IN

Proclinical is seeking a Senior/Principal Protein Scientist to join a dynamic discovery group.

Primary Responsibilities:

The successful candidate will be required to focus on the design, production, and characterization of chemical leads and drug candidates. This role is pivotal in advancing a drug discovery portfolio, particularly in the area of metabolic diseases.

Skills & Requirements:

• Advanced degree in Biochemistry, Biology, Chemistry, or related field.
• Expertise in peptide and protein work, purification, and analytical techniques.
• Proficiency with electronic inventory systems and lab notebooks.
• Strong command of Microsoft Suite.
• Self-starter with excellent problem-solving skills.
• Strong organizational and project management abilities.
• Effective communication and interpersonal skills.
• Experience in peptide and protein modification, biophysical techniques, and drug formulation is preferred.
• Knowledge of drug discovery and development processes is advantageous.

T he Senior/Principal Scientist's responsibilities will be:

• Design and recommend peptides and proteins with therapeutic potential.
• Conduct or coordinate protein expression and purification.
• Perform chemical conjugation or enzymatic ligation of peptides and proteins.
• Purify drug candidates using techniques like RP-HPLC, IEC, or SEC.
• Formulate drug candidates for downstream screening and analysis.
• Characterize synthesized compounds using LCMS, SEC, and SDS-page.
• Conduct biophysical characterization to ensure compounds meet purity and identity standards.
• Analyze data and present findings to multidisciplinary teams.
• Maintain detailed laboratory records and documentation.
• Collaborate with chemists, biologists, and pharmacologists to advance drug candidates.
• Communicate progress and challenges to stakeholders.
• Ensure compliance with regulatory requirements and safety protocols.
• Participate in laboratory inspections and audits.

Compensation:

• $115,000 to $120,000 per annum.

If you are having difficulty in applying or if you have any questions, please contact Sofia Amark at s.amark@proclinical.com

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

INDSCIC

Job Tags

Similar Jobs